Institutions, Health Systems, and Research Consortia

Advarra has built dedicated, specialized capabilities to serve as the IRB of record for dozens of institutional site networks, including therapeutically specialized groups. We support networks ranging in size from 10 sites to 600. Coordinating centers have the visibility and control they need with the Advarra CIRBI Platform. Manage your network studies the way you want with review processes adapted to meet your protocol’s needs.

Public funds account for an important segment of research in Canada and in the United States and leads to crucial discoveries. Advarra pivots smoothly between private and public funding; we apply the same processes and resources to each. Our AAHRPP-accredited IRB complies with the United States’ Common Rule and Canada’s Tri-Council Policy Statement. We can oversee federally funded studies as a local IRB for a single investigator or as the designated single IRB (sIRB) for multisite studies. Advarra reviews research funded by the National Institutes of Health (NIH), Department of Defense (DoD), the Department of Justice (DoJ), the Veterans Administration (VA), the National Science Foundation (NSF), and other government agencies.

Advarra has overseen more than 1,000 federally funded studies and can provide a budget estimate for IRB and more, as well as documentation for your NIH grant application to identify your project’s sIRB and outline responsibilities and communication tactics.

If your institution receives federal funding for multisite research, then you’ll need an sIRB of record. Set your institution up for success by designating Advarra as your sIRB of record. Benefit from our existing processes, procedures, and resources, including budget planning support for grant applications.

Building your own sIRB or serving as a coordinating center for the first time? Empower your institution to thrive in the new sIRB reality. Let Advarra Consulting assess your human research protection program, processes, technology, and documents to help avoid the stress of noncompliance.

There is much to consider when developing a grant application. Maximize your funding request and avoid resource surprises down the line with Advarra’s grant application checklist. When you’re ready, request a budget estimate to include with your application.

Advarra can help sponsor investigators meet the unique challenges and responsibilities of investigator-initiated studies. Your study may be investigator-initiated if you are the primary author of the protocol, if you have initiated the research yourself, or if you are assuming all regulatory responsibilities for the research (i.e., serving as both investigator and sponsor).

Advarra has broad experience in reviewing community-based research conducted in virtually every region of the globe; this experience is as diverse as the patient needs assessments, health determinants, and outcomes in various communities and strata of society. These include studies of substance abuse, domestic violence, gambling, human factors, and educational intervention innovation, among many others. These projects are often publicly funded or funded by the communities themselves with limited governmental or non-governmental organization (NGO) support.