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Oncology Clinical Research

Oncology continues to be one of the most active therapeutic areas in clinical trials. With significant funding from industry and federal agencies, the field is often the first to investigate new treatment modalities, technologies, and discoveries.

With this tradition of innovation comes the challenge of determining how new approaches fit into regulatory plans, clinical operations, and more.

Current Trends and Challenges in Oncology Clinical Research

How is the oncology clinical research community addressing diversity, equity, and inclusion (DE&I)?

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Technology for Conducting Oncology Clinical Trials

Recruitment and retention are particularly challenging when working with very specific inclusion and exclusion criteria. Managing research data can also be difficult, as sites must meet additional reporting requirements from the National Cancer Institute (NCI). And because cancer patients often face grave diagnoses, extra care must be taken to ensure they truly understand what study participation requires.

To find sites with access to the right patient populations, sponsors, and contract research organizations (CROs) may choose to inform feasibility and site selection with site performance data.

Technology like a clinical trial management system (CTMS) can help research sites better manage study activities and report on oncology research data. Automating certain tasks can also help make more time available to focus on participants. However, when sponsors mandate study-specific technology to manage their cancer trials, sites may find the myriad systems a burden. 78% of NCI-designated clinical research sites use Advarra’s OnCore CTMS.

For sites outside of the U.S., sponsors should ensure they provide site-centric and integrated tools to support sites conducting complex research.

20% more enrollment, 50% less screen failure, 21% fewer protocol deviations

Learn how a top-20 pharmaceutical company leveraged the Longboat Platform to facilitate optimal execution and increase engagement for a uniquely challenging global Phase III breast cancer study.

Compliance and Safety in Oncology Clinical Research

Clinical trial safety and compliance are paramount for every type of study, but oncology trials also have special concerns specific to the field.  

30,000+ oncology investigators worldwide rely on Advarra for research participants protections and research performance optimization


Advarra’s Contributions to Oncology Research


of industry-initiated oncology trials in North America rely on Advarra solutions


of NCI designated cancer centers conducting clinical trials are supported by Advarra’s IRB


of NCI designated cancer centers manage their trials with OnCore CTMS

Your Strategic Partner

Successful oncology clinical research begins with proactive expert support: 

Comprehensive safety and ethics reviews for cancer trials

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Proven methodologies for global strategic success

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Standards-based technology solutions to streamline and oversee your oncology portfolio

For Sites   For Sponsors/CROs

Expert professionals to scale site operations, increase research productivity, and exceed goals

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Read our Related Resources


Oncology Innovations and Other Trending Topics from IRB Experts

Join colleagues from NCI-designated cancer centers to discuss the unique ways oncology has pioneered clinical trial advancements.

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Diversity in Cancer Research: Getting Started

Learn how to start ensuring the membership and leadership of your NCI-designated cancer center reflect the population you serve.

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Unique Ethical Issues in Phase I Oncology Studies

An essential step in research, Phase I oncology studies raise unique ethical challenges for sponsors, investigators, and IRBs.

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Ready to make your oncology clinical research safer, smarter, faster?  

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