An Ethics Committee (EC) is a body that reviews research protocols to ensure ethical conduct and participant protections, serving a role similar to an IRB in many countries.
ECs evaluate risk/benefit, informed consent materials, recruitment plans, and safety monitoring approaches before study initiation. They also review amendments and safety updates throughout the study lifecycle. EC approval is typically required for trial activation in jurisdictions that use EC governance models. Independent ethics review supports participant rights, well-being, and ethical research standards globally.