The European Network of Centres for Pharmacoepidemiology and Pharmacovigilance (ENCePP) is an EMA-coordinated network that promotes high-quality post-authorization safety research.
ENCePP develops standards and tools that support methodological rigor, transparency, and independence in observational safety studies. Its principles are frequently used to strengthen study governance, protocol credibility, and public trust in real-world evidence generation. For sponsors operating globally, ENCePP guidance helps align post-market safety activities with European expectations. ENCePP-driven approaches complement U.S. pharmacovigilance requirements and improve consistency across regions.