A Human Research Protection Program (HRPP) is the integrated governance system that coordinates policies, oversight, education, and compliance activities to protect human research participants.
HRPPs typically include IRB operations, investigator responsibilities, training programs, quality assurance, reporting pathways, and institutional leadership accountability. A strong HRPP supports consistent informed consent practices, safety oversight, and ethical decision-making across studies. Many institutions pursue HRPP accreditation to demonstrate programmatic maturity and continuous improvement. Effective HRPP infrastructure strengthens participant protections and supports reliable, compliant study conduct.