Last Twelve Months (LTM) is a financial reporting term that summarizes resultsósuch as revenue or EBITDAóover the most recent 12-month period.
While not a clinical term, LTM metrics may be used by sponsors, CROs, and research institutions to assess operational stability and resource capacity. Financial stability can influence vendor qualification, site sustainability, and the ability to maintain staffing levels required for compliant study conduct. Organizations may use LTM performance to inform investment in technology, quality systems, and training programs. Strong financial governance supports reliable trial delivery by reducing risk of disruptions that could affect participants and study timelines.