The National Cancer Institute (NCI) is a U.S. federal agency and part of the National Institutes of Health that leads national efforts in cancer research, training, and funding.
NCI supports a large clinical trials ecosystem, including cooperative groups, cancer centers, and programs that provide infrastructure for oncology study development and execution. Its resources influence protocol standards, data collection expectations, and operational best practices in cancer research. NCI-backed trials often include centralized oversight, standardized reporting, and robust safety governance to support reliable outcomes. Engagement with NCI programs can expand access to trials and accelerate evaluation of innovative cancer therapies.