A Scientific Review Board (SRB) is a committee that evaluates the scientific merit, feasibility, and appropriateness of proposed research.
SRBs may review study rationale, endpoints, statistical approach, and resource requirements before or alongside ethics review. This review helps ensure studies are scientifically sound and not exposing participants to unnecessary risk for low-value designs. SRB feedback can lead to protocol improvements, clearer objectives, and stronger monitoring plans. Robust SRB processes complement ethics oversight by strengthening scientific validity, which is a core component of ethical research.