A Site Management Organization (SMO) provides operational support services to clinical trial sites, often across multiple locations and studies.
SMOs may assist with staffing, recruitment, regulatory documentation, budgeting support, and day-to-day coordination. Sponsors and CROs use SMOs to scale site capabilities and improve consistency in performance and process execution. Effective SMO governance includes training, quality oversight, and clear delegation to maintain GCP compliance. A well-run SMO can accelerate enrollment and reduce operational variability across site networks.