An Interactive Web Response System (IWRS) is a web-based system used to manage randomization, treatment assignment, and investigational product supply for clinical trials.
IWRS supports protocol-driven enrollment workflows, stratification rules, and real-time inventory management across sites and depots. It is commonly part of an IRT ecosystem and helps maintain blinding by controlling access to allocation information. Sponsors rely on IWRS for accurate tracking of assignments, dosing schedules, and drug accountability metrics. As a regulated computerized system, IWRS must be validated and maintain role-based access, audit trails, and secure data handling to support inspection readiness.