Quality of Life

Abbreviation: QOL

Definition

Quality of Life (QOL) is a multidimensional measure of a personís overall well-being, commonly including physical functioning, emotional health, social functioning, and symptom burden.

In clinical studies, QOL endpoints help quantify treatment impact from the participantís perspective beyond traditional clinical measures. QOL assessments are often captured using validated questionnaires and analyzed as secondary or exploratory endpoints, especially in oncology and chronic disease research. These data can clarify whether clinical benefits translate into meaningful daily-life improvements. Well-designed QOL measurement strengthens patient-centered evidence and supports clearer benefitñrisk communication.

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