An Interactive Voice Response System (IVRS) is a telephone-based technology used to manage trial activities such as randomization, treatment assignment, and certain investigational product logistics.
Site staff interact with IVRS using voice prompts or keypad entries, which enables 24/7 access without requiring web connectivity. IVRS helps maintain blinding and ensures treatment allocation follows protocol-defined rules. These systems often integrate with broader IRT platforms for centralized oversight of enrollment and supply. Validation, access controls, and audit trails are essential to support data integrity and regulatory expectations for computerized systems.