REVIEWS

IRB Services

Institutional Review Board (IRB)

Ensure robust human subject protections and compliant study conduct with reliable IRB services and extensive therapeutic expertise. 

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Advarra’s IRB is the Industry’s Top Choice For:

institutions, site networks, academic medical centers, and hospital systems

of NCI Designated Cancer Centers

of NIH R01 grant-funded leading research institutions

protocols reviewed annually by IRB members

Advarra’s IRB members understand the latest trial designs, therapeutic techniques, and emerging technologies in every clinical trial phase and every device study category.

International IRB Reviews

Advarra has the largest AAHRPP accredited independent REB/IRB in Canada, based in Ontario, which supports research conducted exclusively in Canada as well as cross-border studies. We also offer review services outside of the U.S., Puerto Rico, and Canada.

Flexible Review Schedules

We offer 22 full board meetings Monday through Friday, and minimal risk/expedited reviews are conducted daily. Advarra uses a single IRB roster, rather than dedicated panels, for greater flexibility, expertise, and efficiency.  

Premium Service Comes Standard

Advarra’s IRB has always offered client-focused support at no additional charge to ensure timelines and expectations are met.

Single point of contact who knows your study
 Direct access to dedicated, responsive support  
Reliable review timelines 
Real-time status and rapid document delivery 
One study startup process for all sites 
No submission deadlines 
Rush services available a la carte

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“Advarra provides Academic and Community Cancer Research United (ACCRU) with a thorough review process. This allows us to be more efficient with our study development and startup times. The CIRBI Platform is also easy to use, and the customer service is excellent.”

Brett Percival Coordinator, Regulatory Affairs, Mayo Clinic Cancer Center Clinical Research Office

A Faster Trial Experience With Better Results

IRB Turnaround Times

4–

Business days

New protocol and initial informed consent for multisite studies

(full board review)

1–

Business days

New protocols and initial informed consent for minimal risk review

1–

Business days

New site for a multisite study

Turnaround time is dependent upon complete and accurate submission of study documents. Any follow-up requiring a response may extend this turnaround time.

Manage Your Review in Real Time

The Advarra Center for IRB Intelligence (CIRBI) Platform enables seamless communications and comprehensive reviews of clinical research programs.

Real-time status reporting and rapid document delivery
Start faster with adaptive forms and saved/pre-populated submission data
Centralized communications remove the risk of IRB notices “lost in someone’s email”
Secure 21 CFR Part 11 system that integrates with eReg and eTMF
Technology-enabled IRB processes automate document delivery and support major data connections

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Need the Current IRB Roster?

All IRB rosters are available for direct download in the Reference Materials section of CIRBI (login required).

Alternatively you can request the latest roster here.

Featured Content

Blog

What is an sIRB and Why Does my Study Need One?

Single IRB (sIRB) review streamlines oversight for multisite trials, reducing administrative burdens while ensuring participant protections across all sites.

White Paper

Reporting to the IRB: What Does and Does Not Need to be Reported

Learn the essentials of IRB reporting, including why it matters, what’s required, what’s not, and tips to avoid common reporting challenges.

Blog

Navigating Local Considerations When Developing sIRB Reliance Policies

Implementing an sIRB process requires addressing unique local considerations, from consent requirements to cultural nuances, ensuring a streamlined yet ethical review process.

Info Sheet

Single Institutional Review Board (sIRB) Services Info Sheet

As the research community’s preferred sIRB partner, we help you meet regulatory requirements with efficiency and transparency.

Frequently Asked Questions

Explore our comprehensive FAQ page for detailed answers to questions about our IRB, IBC, DMC, and EAC services.

Find Your Answers

Information for Participants and Patient Advocacy Groups

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Technology-enabled Reviews

Improve compliance and reduce administrative burden with the most integrated reviews solutions in the industry.  

All of our reviews are supported by our best-in-class technology platforms, which provide clients with real-time information on review timelines and deliverables. 

Advarra’s reviews technologies integrate easily into a sponsor’s electronic trial master file (eTMF) platforms and site systems via API. 

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