The University of Maryland Greenbaum Comprehensive Cancer Center (UMGCCC), an NCI-designated cancer center supporting more than 500 active research protocols, sought to modernize fragmented, paper-based regulatory processes to better support operational growth, compliance, and study scalability.

To streamline regulatory document management and improve operational consistency, UMGCCC implemented Advarra eReg, a secure electronic Investigator Site File (eISF) platform integrated with OnCore CTMS. The organization executed a phased enterprise-wide rollout that included migration of more than 38,000 regulatory documents and standardization of regulatory workflows across the cancer center.

Read more about how Advarra eReg helped UMGCCC reduce documentation-related findings by 47.5%, improve binder consistency, streamline regulatory operations, and support continued clinical trial growth through a scalable digital regulatory framework.