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Reliable IRB

Trusted by more institutions than any other IRB, Advarra provides reliable, efficient IRB expertise to protect participants and enable compliance.


A Better Trial Experience for Sites, Participants,
and Study Teams. And Better Results.


business days from submission to review

New protocol and initial
informed consent for multisite
studies (full board review)


business days from submission to review

New protocols and initial
informed consent
(minimal risk review)


business days from submission to review

New site for a multisite

Please note: Turnaround time is dependent upon complete and accurate submission of study documents.
Any follow up requiring a response may extend this turnaround time.

Expert IRB Reviews for Every Phase, Modality, and
Therapeutic Area

Our experience helps accelerate your review

Daily Meetings

With IRB meetings every business day, daily minimal risk reviews, and ad-hoc reviews as needed, there’s no need to worry about submission deadlines. We’ll make it happen.

Expertise in Every Therapeutic Area and Modality

Our members understand the latest therapeutic techniques, emerging technologies, and innovative trial designs: precision medicine, AI and machine learning, remote and hybrid trials, devices and digital therapeutics, Phase I, pediatrics, federally funded studies, exemptions, mRNA clinical trials, EFIC studies, cell and gene therapies, retrospective chart review, complex protocol design and adaptive trials…you get the idea.

The Most Integrated IRB

With technology-enabled IRB processes, it’s easy to automate document delivery and other data connections. Advarra Connect replaces manual, error-prone processes by automating the secure transfer of IRB-related documents directly to your eTMF or eReg system.

More Institutional Relationships Than Any Other IRB

3,500+ institutions, site networks, academic medical centers, and hospital systems work with Advarra. Our team includes local IRB expats and institutional research leaders, and we work with you to tailor services that meet local context requirements.

Real-Time Status Information

No IRB “black box” here – our CIRBI Platform provides real-time updates with consolidated central communications so you don’t have to hunt down your IRB review documentation.

International IRB Reviews

Based in Ontario, Advarra has the largest AAHRPP accredited independent REB/IRB in Canada support both research conducted exclusively in Canada as well as cross-border studies.

For research conducted outside North America, Advarra has experience reviewing international studies and can support it in the following ways:

  • Review to ensure compliance with US standards (with local ethics committee review)
  • Collaborate with local ethics committee review
  • Serve as the sole IRB of record for online research not targeted at a specific country and certain other minimal risk research
  • Advarra can translate informed consent forms (ICFs) and other study documents into the appropriate languages. We can also provide consulting services to help you prepare for research abroad and assess local regulatory requirements.
    *Note: Advarra does not review research conducted in India.

Learn More About IRB Review of International Research

Need the Current IRB Roster?

Login to the Advarra CIRBI Platform and select the “Reference Materials” tab

Request the latest IRB roster

Get Answers to Common Questions About Our Independent IRB

Are You a Research Participant?

Find out how the IRB helps protect
your rights and welfare.

Ensure You Have Everything
You Need For Your New
Study Submission.